CBD is supported by scientific evidence for the following benefits, though in some cases, more research is needed. Consult with your health care provider before using CBD as a treatment option.
1. Pain Relief
According to Jessica Plonchak, a licensed clinical alcohol and drug counselor and clinical director at ChoicePoint Health, CBD modulates ECS receptors (CB1 & CB2), serotonin receptors and TRPV1 receptors, all of which are involved in sending pain signals in the body.
Research suggests that CBD may be effective in alleviating various types of pain, including fibromyalgia, arthritis, cancer-related pain and neuropathic pain. The authors of a 2025 review published Biomolecules concluded that while CBD shows promise as a chronic pain management alternative to traditional pain medications like opioids, more research is needed.
2. Anxiety Reduction
CBD has been used to alleviate anxiety because of its soothing properties, says Hamilton Gaiani, MD, a double-board-certified psychiatrist and chief medical officer at Firepit Health. “CBD is thought to exert its [anxiety-reducing] effect by binding to the brain’s serotonin receptors,” he explains.
A small 2019 study published in The Permanente Journal found that CBD significantly decreased anxiety levels in 79% of participants. And a 2020 review in The Canadian Journal of Psychiatry found that CBD may improve symptoms of anxiety and depression in individuals with mood disorders, although more research is needed.
3. Improved Sleep
CBD may also contribute to better sleep quality, particularly in individuals with insomnia caused by anxiety and trauma, says Dr. Gaiani. It’s believed that CBD’s relaxing effects on the body and mind can help promote a restful night’s sleep. A 2019 study in The Permanente Journal found that CBD improved sleep scores in patients with anxiety and poor sleep quality.
4. Reduces Inflammation
CBD’s anti-inflammatory properties make it a potential treatment for various inflammatory conditions, such as arthritis, inflammatory bowel disease and multiple sclerosis. A 2022 review in Frontiers in Pharmacology concluded that CBD may reduce inflammation by stopping the production of pro-inflammatory cytokines (a group of signaling molecules that amplify inflammation in the body), but more research is needed to understand its exact mechanism of action.
5. Seizure Management
One of the most well-documented benefits of CBD is its effectiveness in managing seizures, particularly in children and adults with epilepsy. Epidiolex, a CBD-based medication, is FDA-approved for the treatment of Dravet syndrome and Lennox-Gastaut syndrome, two rare forms of epilepsy, in patients older than 2. According to a 2019 review in Molecules, clinical trials have demonstrated that CBD can significantly reduce the frequency and severity of seizures.
6. Cancer Symptom Relief
For individuals undergoing cancer treatment, CBD may help alleviate chemotherapy-induced nausea and vomiting. A 2020 study in Annals of Oncology found that individuals who received a combination of CBD and THC experienced significant relief from these symptoms, with 25% experiencing no vomiting or nausea compared to 14% who received a placebo. Although the results are promising, the researchers plan to conduct further testing.
7. Helps With Neurological Disorders
CBD has shown promise in treating various neurological disorders, including multiple sclerosis (MS), Parkinson’s disease, Alzheimer’s disease and Huntington’s disease. Research indicates that CBD can help reduce muscle spasms and improve mobility in MS patients. A 2022 review in Frontiers in Pharmacology found that CBD may protect neurons and reduce neuroinflammation, potentially benefiting those with neurodegenerative disorders.
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